product summary
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company name :
MyBioSource
product type :
antibody
product name :
EEA1 Polyclonal Antibody
catalog :
MBS448005
quantity :
0.6 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunocytochemistry
more info or order :
image
image 1 :
image 2 :
product information
catalog number :
MBS448005
products type :
Antibody
products full name :
EEA1 Polyclonal Antibody
products short name :
[EEA1]
products name syn :
[Anti-EEA1; Early endosome antigen 1,162kD; early endosome-associated protein; endosome-associated protein p162; zinc finger FYVE domain-containing protein 2 antibody]
other names :
[early endosome antigen 1; Early endosome antigen 1; early endosome antigen 1; early endosome antigen 1, 162kD; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2; early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2]
products gene name :
[EEA1]
other gene names :
[EEA1; EEA1; MST105; ZFYVE2; MSTP105; ZFYVE2]
uniprot entry name :
EEA1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Goat
reactivity :
human, rat, mouse, canine and monkey proteins.
sequence length :
1411
specificity :
Detects a band of 180 kDa by Western blot in the following human, mouse and rat whole cell lysates.
form :
Polyclonal antibody supplied as (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
storage stability :
For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.
tested application :
Immunofluorescence (IF), Western Blot (WB)
app notes :
Western Blot: 1:250-1:1,000. Immunofluorescence: 1:50-1:250
image1 heading :
Reactivity Chart
image2 heading :
Testing Data
other info1 :
Gene Identifier: ENSG00000102189. Immunogen: Purified recombinant peptide within residues 1,230 aa to the C-terminus of human EEA1 produced in E. coli.
other info2 :
Handling: The antibody solution should be gently mixed before use.
products description :
Early Endosome Antigen 1. Goat polyclonal antibody to EEA1 - early endosome marker. EEA1 is Early Endosome Antigen 1 protein that binds phospholipid vesicles containing phosphatidylinositol 3-phosphate, which is necessary for endosomal trafficking.
ncbi gi num :
55770888
ncbi acc num :
NP_003557.2
ncbi gb acc num :
NM_003566.3
uniprot acc num :
Q15075
ncbi mol weight :
162,466 Da
ncbi pathways :
Endocytosis Pathway (102279); Endocytosis Pathway (102181); Immune System Pathway (106386); Innate Immune System Pathway (106387); Phagosome Pathway (153910); Phagosome Pathway (153859); Toll Like Receptor 9 (TLR9) Cascade Pathway (106397); Toll-Like Receptors Cascades Pathway (106388); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
uniprot summary :
Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Subunit structure: Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with RAB31. Interacts with ERBB2. May interact with PLEKHF2. Ref.5 Ref.6 Ref.7 Ref.8 Ref.9 Ref.10 Ref.11 Ref.12 Ref.13 Ref.17 Ref.18. Subcellular location: Cytoplasm. Early endosome membrane; Peripheral membrane protein Ref.1 Ref.7 Ref.9 Ref.13 Ref.17. Domain: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns3P-enriched membranes is substantially increased in acidic conditions. Ref.14. Miscellaneous: Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. Sequence similarities: Contains 1 C2H2-type zinc finger.Contains 1 FYVE-type zinc finger.
size1 :
0.6 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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