product summary
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company name :
MyBioSource
product type :
protein
product name :
VEGF (A19) Blocking Peptide
catalog :
MBS443051
quantity :
0.1 mg
price :
125 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS443051
products type :
Peptide
products full name :
VEGF (A19) Blocking Peptide
products short name :
VEGF
other names :
Vascular endothelial growth factor A; Vascular permeability factor; VPF
products gene name :
VEGF
other gene names :
VEGFA; VEGF; VEGF-A; VPF
uniprot entry name :
VEGFA_HUMAN
clonality :
Polyclonal
host :
Rabbit
sequence length :
317
specificity :
GST fusion proteins
concentration :
0.100 mg/0.5 ml
storage stability :
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
other info1 :
Origin: VEGF (A19) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to a domain near the amino terminus of Human VEGF.
other info2 :
Immunogen: Purified glutathione-S-transferase (GST) from Schistosoma japonicum
products categories :
Controls
products description :
The vascular endothelial growth factor (VEGF) family currently includes VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF (1). VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis (2). Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process (3&4). To date 5 different isoforms of VEGF have been described, VEGF 121, VEGF 145, VEGF 165, VEGF 165b, and VEGF 189(4&5). These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells (5).
products references :
1. Matsumoto T, Claesson-Welsh L. 2001. VEGF receptor signal transduction. Sci STKE 112:RE21.2. Shibuya M. 2001. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct 26(1):25-35.3. Hasan J, Jasyson GC. 2001. VEGF antagonists. Expert Opin Biol Ther 1(4):703-18.4. Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. 2002. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res 62(14):4123-31.5. Neufel G, Cohen T, Gengrinovitch S, Poltorak Z. 1999. Vascular endothelial growth factor (VEGF) and its receptors. FASEB 13(1):9-22.
ncbi gi num :
220732299
ncbi acc num :
CAC19513.2
uniprot acc num :
P15692
ncbi mol weight :
34,406 Da
size :
0.1 mg
price :
125 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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