product summary
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company name :
MyBioSource
product type :
antibody
product name :
Monocloncal Antibody Aggrecan (Clone 6B4)
catalog :
MBS442006
quantity :
0.1 mg
price :
405 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6B4
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS442006
products type :
Antibody
products full name :
Monocloncal Antibody Aggrecan (Clone 6B4)
products short name :
Aggrecan IGD
products name syn :
Aggrecan IGD Antibody
clonality :
Monoclonal
isotype :
IgG1
clone :
6B4
host :
Mouse
reactivity :
Human, bovine
specificity :
Recognizes the linear amino acid sequence 394EPEEPFTFAPEI406 present in the interglobular domain (IGD) of human and bovine aggrecan.
purity :
Affinity purified on protein G
form :
Liquid, 1 mL/vial
concentration :
0.1 mg/mL
storage stability :
Store at -20 degree C.
tested application :
ELISA (EIA), Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB)
app notes :
ELISA: Use at an assay dependant dilution.; IHC-P: Use at an assay dependant dilution.; IHC-Fr; Use at an assay dependant dilution.; WB: Use at a dilution of 1/100.
other info1 :
Immunogen: Synthetic peptide: EPEEPFTFAPEI. Myeloma: x63-Ag8.653. Light Chain Type: kappa
other info2 :
Technical Notes: Optimal dilutions/concentrations should be determined by the end user. This antibody should work in IHC on formalin or paraformaldehyde-fixed paraffin embedded sections as well as either alcohol-fixed frozen sections or un-fixed snap-frozen sections. Samples are usually deglycosylated using 0.01 Units Chondroitinase ABC (Sigma), 0.01 Units Keratanase (Seikagaku) and 0.0001 Units Keratanase II (Seikagaku) per 10ug S-GAG of non-deglycosylated aggrecan for optimal epitope recognition in SDS-PAGE and immunohistochemistry.
products categories :
Antibodies to Aggrecan
products description :
Aggrecan IGD monoclonal antibody (mouse, clone 6B4). This antibody detects aggrecan metabolites (intact or matrix protease-catabolised) in human synovial fluid samples. Overview: Proteoglycans are categoried depending upon the nature of their glycosaminoglycan chains (chondroitin sulfate, dermatan sulfate, heparan sulphate and keratan sullfate) as well as characterized by size. Aggrecan is a large aggregating proteoglycan of articular cartilage. It is found also in aorta tissue, discs, tendons and in the perineuronal net. It is responsible for hydrating cartilage, giving it compressibility and resiliance during joint loading, thereby playing a major role in the normal function of cartilage. Depletion of glycosaminoglycan bearing aggrecan fragments is one of the earliest events in cartilage destruction. A) Aggrecan monomer showing proteolytic cleavage sites B) Aggregate showing aggrecan monomers bound to hyaluronic acid
size :
0.1 mg
price :
405 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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