catalog number :
MBS440107
products full name :
Protein C-tag (E12) Antibody
products short name :
Protein C
other names :
protein C, partial; Vitamin K-dependent protein C; vitamin K-dependent protein C; anticoagulant protein C; autoprothrombin IIA; blood coagulation factor XIV; prepro-protein C; type I protein C; protein C (inactivator of coagulation factors Va and VIIIa); Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV
other gene names :
PROC; PROC; PC; APC; PROC1; THPH3; THPH4
uniprot entry name :
PROC_HUMAN
specificity :
Detects proteins with the Protein C-tag, EDQVDPRLIDGK
form :
200 ug/ml rabbit polyclonal IgG in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin.
concentration :
0.200 mg/ml
storage stability :
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Protein C-tag (E12) DB119 is recommended for use by western blotting and ELISA. The suggested western blotting starting dilution is at 1:400.
other info1 :
Origin: Protein C-tag (E12) is provided as an affinity purified rabbit polyclonal raised against a synthetic peptide, EDQVDPRLIDGK, derived from the heavy chain of human Protein C.
other info2 :
Immunogen: Synthetic peptide EDQVDPRLIDGK
products description :
Protein C is a vitamin K-dependent serine protease that regulates blood coagluation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
products references :
1.) Kamil JP, Coen DM. 2007. Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65. J Virol. Oct;81(19):10659-68.
ncbi acc num :
AAB25410.1
ncbi mol weight :
57,556 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway 106062!!Common Pathway Of Fibrin Clot Formation 106060!!Complement And Coagulation Cascades Pathway 198880!!Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Formation Of Fibrin Clot (Clotting Cascade) Pathway 106057!!Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway 106231!!Gamma-carboxylation Of Protein Precursors Pathway 106233!!Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway 106232!!Hemostasis Pathway 106028
ncbi summary :
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]