product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Neu (C18) Antibody
catalog :
MBS440046
quantity :
0.2 mg
price :
240 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS440046
products type :
Antibody
products full name :
Neu (C18) Antibody
products short name :
Neu
clonality :
Polyclonal
host :
Rabbit
reactivity :
Mouse, rat, human
specificity :
Mouse, rat, and human Neu
form :
Each vial contain 200ug/ml of affinity purified rabbit IgG Neu (C18), in 1ml PBS containing 0.1% sodium azide and 0.2% gelatin.
concentration :
0.200 mg/ml
storage stability :
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
tested application :
Western Blot (WB), Immunopreciptation (IP), Immunohistochemistry (IHC) Paraffin
app notes :
Western blot analysis of Neu expression in SK-BR-3 whole cell lysates. Western Blotting: 1:200
other info1 :
Origin: Neu (C18) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to the carboxy terminus of human Neu (HER2 or ErbB-2).
other info2 :
Immunogen: Synthetic peptide mapping to the carboxy terminus of human Neu (HER2 or ErbB-2). Competition studies: A blocking peptide is also available for use in competition studies. Each vial contains 100ug of peptide in 0.5ml PBS with 0.1% sodium azide and 100 ug BSA.
products description :
The Neu/HER-2 (also known as EGFR-2 or ErbB-2) is a transmembrane tyrosine kinase receptor and a well-defined tumor antigen. Neu/HER-2 is a shared antigen among multiple tumor types. Patients with HER-2/neu protein-overexpressing breast, ovarian, non-small cell lung, colon, and prostate cancers have been shown to have a pre-existent immune response to Neu/HER-2 (1,2). Neu/HER-2 amplification/overexpression confers more aggressive and malignant characteristics on breast cancer cells. Patients with Neu/HER-2-amplified breast cancer have a worse prognosis than those with normal Neu/HER-2 expression (3).
products references :
1. Bernhard H, Salazar L, Schiffman K, Smorlesi A, Schmidt B, Knutson KL, Disis ML. Vaccination against the HER-2/neu oncogenic protein. Int J Endocr Relat Cancer 2002 Mar;9(1):33-44.2. Lohrisch C, Piccart M. HER2/neu as a predictive factor in breast cancer. Clin Breast Cancer 2001 Jul;2(2):129-35; discussion 136-7.3. Hortobagyi GN. Overview of treatment results with trastuzumab (Herceptin) in metastatic breast cancer. Semin Oncol 2001 Dec;28(6 Suppl 18):43-7
size1 :
0.2 mg
price1 :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!