Cd90 | MyBioSource MBS438440 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Cd90

catalog :

MBS438440

quantity :

0.02 mg (With BSA & Azide at 0.2 mg/ml)

price :

190 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[F15-42-1]

reactivity :

human

application :

immunocytochemistry, flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS438440

products type :

Antibody

products full name :

Cd90

products short name :

[Cd90]

products name syn :

[CD90; Theta antigen; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1.2; Thy-1 antigen; Thy-1 membrane glycoprotein; Thy1; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta]

other names :

[thy-1 membrane glycoprotein preproprotein; Thy-1 membrane glycoprotein; thy-1 membrane glycoprotein; CDw90; thy-1 antigen; Thy-1 T-cell antigen; Thy-1 cell surface antigen; CDw90; Thy-1 antigen; CD_antigen: CD90]

products gene name :

[THY1]

other gene names :

[THY1; THY1; CD90]

uniprot entry name :

THY1_HUMAN

clonality :

Monoclonal

isotype :

IgG1, kappa

clone :

[F15-42-1]

host :

Mouse

reactivity :

Human, Monkey. Others not known.

sequence length :

161

specificity :

CD90 (Thy-1) is an 18-35kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.

form :

200 ug/mL of AB purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% Azide.

storage stability :

Antibody with azide store at 2-8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

tested application :

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies (Order Ab without BSA % Azide).

app notes :

Flow Cytometry (0.5-1 ug/million cells). Immunofluorescence (0.5-1 ug/mL). Functional studies (Order Ab without BSA & Azide). Optimal dilution for a specific application should be determined.

other info1 :

Localization: Cell surface. Positive Control: IMR-32, CCRF-CEM or MOLT-4 Cells. Human Uterus. Human Chromosomal Location: 11q23.3

other info2 :

Immunogen: Purified human brain Thy1

products references :

1. Cervelló I et al. Reconstruction of endometrium from human endometrial side population cell lines. PLoS One6:e21221 (2011). 2. Lehmann GM et al. Novel anti-adipogenic activity produced by human fibroblasts. Am J Physiol Cell Physiol299:C672-81 (2010).

ncbi gi num :

19923362

ncbi acc num :

NP_006279.2

ncbi gb acc num :

NM_006288.3

uniprot acc num :

P04216

ncbi mol weight :

18-35kDa

ncbi pathways :

Cardiac Progenitor Differentiation Pathway (712094); IL4-mediated Signaling Events Pathway (137933); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Amb2 Integrin Signaling Pathway (137945)

ncbi summary :

This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

uniprot summary :

THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Protein type: Cell adhesion; Membrane protein, GPI anchor; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 11q23.3. Cellular Component: anchored to external side of plasma membrane; growth cone; focal adhesion; integral to plasma membrane; endoplasmic reticulum; apical plasma membrane; dendrite; plasma membrane; cytosol; external side of plasma membrane; lipid raft. Molecular Function: integrin binding; protein binding; protein kinase binding. Biological Process: focal adhesion formation; negative regulation of T cell receptor signaling pathway; cytoskeleton organization and biogenesis; T cell receptor signaling pathway; cell-cell adhesion; retinal cone cell development; negative regulation of protein kinase activity; negative regulation of axonogenesis; positive regulation of release of sequestered calcium ion into cytosol; angiogenesis; positive regulation of T cell activation; negative regulation of cell migration; positive regulation of GTPase activity

size1 :

0.02 mg (With BSA & Azide at 0.2 mg/ml)

price1 :

190 USD

size2 :

0.1 mg (With BSA & Azide at 0.2mg/ml)

price2 :

340

size3 :

0.1 mg (Without BSA & Azide at 1mg/ml)

price3 :

340

more info or order :

MyBioSource product webpage