product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mannose Receptor (MRC1) Rabbit mAb
catalog :
MBS435207
quantity :
0.02 mL
price :
225 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS435207 image 1
Western Blot analysis of MRC 1 expression in 293T cell lysate
product information
catalog number :
MBS435207
products type :
Antibody
products full name :
Mannose Receptor (MRC1) Rabbit mAb
products short name :
[Mannose Receptor (MRC1)]
products name syn :
[Macrophage mannose receptor 1; MMR; CD206 antigen; MRC1; Mannose receptor C type 1.]
other names :
[macrophage mannose receptor 1; Macrophage mannose receptor 1; macrophage mannose receptor 1; mannose receptor C-type 1; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor; hMR; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206]
products gene name :
[MRC1]
products gene name syn :
[CD206; MMR; CLEC13D; CLEC13DL; MRC1L1]
other gene names :
[MRC1; MRC1; MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; CLEC13D; CLEC13DL; MRC1L1; MMR; hMR]
clonality :
Monoclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
1456
purity :
Affinity-chromatography
form :
Liquid; pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
app notes :
WB: 1:500-1:2000. ICC/IF: 1:50-1:200
image1 heading :
Western Blot (WB)
other info1 :
Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to Mannose Receptor (MRC1) protein. Immunogen: A synthesized peptide
products categories :
CD Marker; Subcellular Marker; Membrane
products description :
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
ncbi gi num :
4505245
ncbi acc num :
NP_002429.1
ncbi gb acc num :
NM_002438.3
uniprot acc num :
P22897
ncbi mol weight :
166kDa
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway (477126); Immune System Pathway (106386); Phagosome Pathway (153910); Phagosome Pathway (153859); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
uniprot summary :
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.(Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.(Microbial infection) Acts as a receptor for Dengue virus envelope protein E.
size1 :
0.02 mL
price1 :
225 USD
size2 :
0.05 mL
price2 :
350
size3 :
0.1 mL
price3 :
565
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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