catalog number :
MBS434232
products type :
Recombinant Protein
products full name :
HCV E2 protein (aa 383-663), Subtype 1a
products short name :
[HCV E2 protein]
products name syn :
[HCV E2 protein; subtype 1a; HCV E2 PROTEIN; HCV E2 protein]
sequence :
AETHVTGGSAGRTTAGLVGLLTPGAKQNIQLINTNGSWH
INSTALNCNESLNTGWLAGLFYQHKFNSSGCPERLASCR
RLTDFAQGWGPISYANGSGLDERPYCWHYPPRPCGIVPA
KSVCGPVYCFPSPVVVGTTDRSGAPTYSWGANDTDVFVL
NNTRPPLGNWFGCTWMNSTGFTKVCGAPPCVIGGVGNNT
LLCPTDCFRKHPEATYSRCGSGPWITPRCMVDYPYRLWH
YPCTINYTIFKVRMYVGGVERLEAACNWTRGERCDLEDR
DRSELS
concentration :
1 ug/ul in PBS with 20% glycerol and 0.1% sodium azide.
storage stability :
Store at -20 degree C. Stable for 3-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
tested application :
Western Blot (WB), Antigen, ELISA (EIA)
image1 heading :
SDS-PAGE
other info1 :
Note: Viral protein purified from 293 cell culture (heavily N-glycosylated)
other info2 :
Endotoxin Level: <0.01 EU per 1 ug of the protein by LAL test. Viral Protein: C-terminal 6xHis tagged HCV E2 protein (amino acid 383-663) (Genebank No. AF009606), subtype 1a
products categories :
Viral Recombinant Proteins; Hepatitis Virus
products description :
Description: 6xHis tagged HCV E2 protein (aa 383-663)(subtype 1a) expressed in 293 cells (Genebank Accession No. AF009606). Viral protein purified from 293 cell culture (heavily N-glycosylated). Introduction: The hepatitis C virus (HCV) is a small, enveloped, single-stranded, positive-sense RNA virus. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. There are seven major genotypes of HCV with several subtypes within each genotype. The viral RNA codes for a large polyprotein of approx. 3100 amino acids, which is posttranslationally processed by cellular and viral proteases. The N-terminus encompasses the structural proteins core and two glycoproteins (E1, E2); the C-terminus encompasses the p7 protein and the nonstructural (NS) proteins NS2, NS3, NS4A, NS4B, NS5A and NS5B.