product summary
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company name :
MyBioSource
product type :
protein
product name :
SIV gp120 (Isolate SIVmac251v31523ru28) (aa 31-528)
catalog :
MBS434203
quantity :
0.05 mg
price :
470 USD
more info or order :
image
image 1 :
purified SIV gp120 protein (isolate SIVmac251v31523ru28)
product information
catalog number :
MBS434203
products type :
Recombinant Protein
products full name :
SIV gp120 (Isolate SIVmac251v31523ru28) (aa 31-528)
products short name :
[SIV gp120]
products name syn :
[gp120 (SIV/mac251)(isolate SIVmac251v31523ru28); SIV Envelop Protein gp120 (Isolate SIVmac251v31523ru28); gp120 (SIV/mac251)(isolate SIVmac251v31523ru28)]
products gene name :
[SIV gp120]
host :
293 cell culture
purity :
>= 95% purity(SDS-PAGE)
concentration :
1 mg/mL in PBS.
storage stability :
Store at -20°C. Stable for 3-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
tested application :
Western Blot standard, antibody ELISA, HIV-1 entry inhibition, etc.
app notes :
SDS-PAGE Data: purified SIV gp120 protein (isolate SIVmac251v31523ru28)
image1 heading :
SDS-PAGE
other info2 :
Viral Protein: 6xHis tagged gp120 (SIV/mac251)(isolate SIVmac251v31523ru28) protein (amino acid 31-528) (Genebank accession#: GU952740)
products categories :
Viral Recombinant Proteins; HIV/SIV
products description :
6xHis tagged gp120 (SIV/mac251)(isolate SIVmac251v31523ru28) (aa 31-528)(Genebank No. GU952740)purified from 293 cell culture. Envelope protein gp120 expressed and purified from 293 cell culture. Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120. Gp120 is essential for virus entry into cells as it plays a vital role in attachment to specific cell surface receptors. These receptors are DC-SIGN, Heparan Sulfate Proteoglycan and a specific interaction with the CD4 receptor, particularly on helper T-cells. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral with the host cell membrane. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.
products references :
1. Stone, M., etc. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251. J. Virol. 84 (14), 7083-7095 (2010). 2. Manrique, M., etc. Resistance to infection, early and persistent suppression of SIVmac251 viremia and significant reduction of tissue viral burden after mucosal vaccination in females Rhesus macaques. J Virol. 2013 Oct 23
size1 :
0.05 mg
price1 :
470 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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