product summary
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company name :
MyBioSource
product type :
protein
product name :
gp120 (JRFL) (HIV-1/Clade B) (aa 34-518)
catalog :
MBS434050
quantity :
0.05 mg
price :
365 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS434050
products type :
Recombinant Protein
products full name :
gp120 (JRFL) (HIV-1/Clade B) (aa 34-518)
products short name :
gp120 (JRFL) (HIV-1/Clade B)
products name syn :
gp120 (JRFL) (HIV-1/Clade B) (aa 34-518); glycosylated recombinant protein; gp120 (JRFL) (Clade B); gp120 (JRFL) (HIV-1/Clade B) (aa 34-518), glycosylated recombinant protein
other names :
HIV-1 isolate JRFL (USA) gag, pol, vif, vpr, tat, rev and env genes, complete cds; Envelope glycoprotein gp160; Endogenous retrovirus group K member 113 Env polyprotein
products gene name :
gp120
other gene names :
env
uniprot entry name :
Q75760_9HIV1
host :
293 cell culture
sequence length :
8896
purity :
>= 95% (SDS-PAGE)
concentration :
1 ug/ul in PBS
storage stability :
Store at -20 degree C. Stable for 6-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
tested application :
Western Blot Standard (WB), antibody ELISA (EIA), HIV-1 entry inhibition, Immunogen, etc.
app notes :
SDS-PAGE Data: Purified HIV-1 gp120 (JRFL) (Clade B) protein
other info2 :
Endotoxin Level: <0.01 EU per 1 ug of the protein by LAL test. Viral Protein: 6xHis tagged HIV-1 gp120 (JRFL) (Clade B) protein (amino acid 34-518) (Genebank No. U63632).
products categories :
Viral Recombinant Proteins; HIV/SIV
products description :
Description: 6xHis tagged HIV-1 gp120 (JRFL) (Clade B) protein (amino acid 34-518) (Genebank No. U63632). Viral protein purified from 293 cell culture. Introduction: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120. Gp120 is essential for virus entry into cells as it plays a vital role in attachment to specific cell surface receptors. These receptors are DC-SIGN, Heparan Sulfate Proteoglycan and a specific interaction with the CD4 receptor, particularly on helper T-cells. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral with the host cell membrane. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.
ncbi gi num :
1465777
ncbi acc num :
AAB05604.1
ncbi mol weight :
96,160 Da
size1 :
0.05 mg
price1 :
365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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