catalog number :
MBS434003
products type :
Recombinant Protein
products full name :
E2 (HCV) (amino acid 383-663), subtype 1b
products short name :
E2 (HCV)
products name syn :
HCV E2 protein; subtype 1b; E2 (HCV); Subtype 1b; Hepatitis C Virus E2 Recombinant Protein
other names :
Hepatitis C virus from Shanghai, complete genome; Genome polyprotein
uniprot entry name :
Q6SCJ5_9HEPC
sequence :
GQTRAVGGMQSHFTQRFVSLFSLGPAQKIQLVNTNGSWH
VNRTALNCNDSLQTGFIAALFYANRFNSSGCPERLASCR
PIDKFAQGWGPITYAKPDSPDQRPYCWHYAPQPCGIVPA
SEVCGPVYCFPSPVVVGTPIRFGVPTYTWGANETDVLLL
NNTRPPLGNWFGCTWMNATGFTKTCGGPPCNIGGVGNNA
LTCPTDCFRKHPEATYAKCGSGPWLTPRCMVDYPYRLWH
YPCTVNFTIFKVRMYVGGVERLNAACNWTRGERCNLEDR
DRSELS
purity :
> = 96% purity (by SDS-PAGE)
concentration :
1 ug/ul in PBS with less than 0.1% BSA and 25% glycerol
storage stability :
Store at -20 degree C. Stable for 6-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
tested application :
Western Blot (WB), ELISA (EIA), Antigen.
other info1 :
Note: Viral protein purified from 293 cell culture.
other info2 :
Endotoxin Level: <0.01 EU per 1 mug of the protein by LAL test. Viral Protein: C-terminal 6xHis tagged HCV E2 protein (amino acid 383-663) (subtype 1b) (Genebank No. AY460204).
products categories :
Viral Recombinant Proteins; Hepatitis Virus
products description :
Description: 6xHis tagged HCV E2 protein (amino acid 383-663) (Genebank Accession No. AY460204) expressed in 293 cells. Viral protein purified from 293 cell culture. Introduction: The hepatitis C virus (HCV) is a small, enveloped, single-stranded, positive-sense RNA virus. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. There are seven major genotypes of HCV with several subtypes within each genotype. The viral RNA codes for a large polyprotein of approx. 3100 amino acids, which is posttranslationally processed by cellular and viral proteases. The N-terminus encompasses the structural proteins core and two glycoproteins (E1, E2); the C-terminus encompasses the p7 protein and the nonstructural (NS) proteins NS2, NS3, NS4A, NS4B, NS5A and NS5B.
ncbi acc num :
AAR22408.1
ncbi mol weight :
326,746 Da