catalog number :
MBS432100
products full name :
Anti-H1 (H1N1)(A/Brisbane/59/2007)
products short name :
[H1 (H1N1)(A/Brisbane/59/2007)]
products name syn :
[Anti-H1(H1N1)(A/Brisbane/59/2007); Anti-H1 (A/Brisbane/59/07)(H1N1) rabbit polyclonal antibody]
other names :
[hemagglutinin; Hemagglutinin]
products gene name :
[H1]
uniprot entry name :
B0VX46_9INFA
specificity :
Reacts with H1 (A/Brisbane/59/07)(H1N1) and related H1.
purity :
Immunoaffinity chromatography
concentration :
2 mug/mul in PBS.
storage stability :
Store at -20 degree C. Stable for 6-months from the date of shipment when kept at - 4 degree C. Non-hazardous. No MSDS required.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
ELISA: 1:1000-1:100,000. Western Blot Data: Lane1, HA protein (aa 18-530)(A/Brisbane/59/2007)(H1N1). Lane2, HA1 protein (aa 18-343)(A/Brisbane/59/2007)(H1N1)
image1 heading :
Testing Data
other info2 :
Immunogen: DNA vaccine expressing H1 (A/Brisbane/59/07)(H1N1) (Genebank No. ACA28846)
products categories :
Antibodies for Infectious Diseases (rabbit polyclonal unless specified); Affinity Purified Rabbit Polyclonal Antibodies against Influenza A
products description :
Description: Anti-H1 (A/Brisbane/59/07)(H1N1) rabbit polyclonal antibody
ncbi acc num :
ACA28846.1
ncbi mol weight :
63,196 Da
uniprot summary :
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.