catalog number :
MBS428588
products type :
Blocking Peptide
products full name :
cytokeratin 19 Immunizing Peptide
products short name :
[cytokeratin 19]
products name syn :
[KRT19; keratin 19; CK19; K19; K1CS; 40-kDa keratin intermediate filament; CK-19; cytokeratin 19; cytokeratin-19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Cytokeratin 19; cytokeratin 19]
other names :
[keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 19; keratin, type I cytoskeletal 19; keratin 19; Cytokeratin-19; CK-19; Keratin-19; K19]
products gene name :
[KRT19]
other gene names :
[KRT19; KRT19; K19; CK19; K1CS; CK-19; K19]
uniprot entry name :
K1C19_HUMAN
sequence :
C-EGQEDHYNNLSASK
form :
100ug of lyophilized peptide, formulation 5pmol/ul in 5% (v/v) acetonitrile/H2O. Reconstitute pellet in distilled water where required. For blocking studies, reconstitute pellet in 200 ul distilled water to obtain a 0.5 mg/ml peptide solution.
storage stability :
Shipped at ambient temperature, store at -20°C
app notes :
The peptide was used in the production of Goat Anti-cytokeratin 19 antibody. It is currently untested in blocking applications.
ncbi acc num :
NP_002267.2
ncbi gb acc num :
NM_002276.4
ncbi mol weight :
44,106 Da
ncbi pathways :
Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
ncbi summary :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
uniprot summary :
K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: costamere; dystrophin-associated glycoprotein complex; intermediate filament; plasma membrane; sarcolemma; Z disc. Molecular Function: protein binding; protein complex binding; structural constituent of cytoskeleton; structural constituent of muscle. Biological Process: Notch signaling pathway; response to estrogen stimulus; sarcomere organization; viral reproduction