protein

ABCC3 Immunizing Peptide

MBS427782

0.1 mg

190 USD

Peptide

ABCC3 Immunizing Peptide

ABCC3

ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABC31; DKFZp686E22157; EST90757; MLP2; MOAT-D; MRP3; cMOAT2; ATP-binding cassette sub-family C member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic; ABCC3

canalicular multispecific organic anion transporter 2 isoform 1; Canalicular multispecific organic anion transporter 2; canalicular multispecific organic anion transporter 2; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3

ABCC3

ABCC3; ABCC3; MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757; CMOAT2; MLP2; MRP3; MOAT-D

MRP3_HUMAN

Human, Mouse, Dog, Pig, Cow

1527

C-DTLSNHTDLTDNDP

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

9955970

NP_003777.2

NM_003786.3

64,632 Da

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (1269904); Bile Acid And Bile Salt Metabolism Pathway (1270040); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Codeine And Morphine Metabolism Pathway (198831); Drug Induction Of Bile Acid Pathway (698755); Fluoropyrimidine Activity Pathway (198778); Metabolism Pathway (1269956)

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

ABCC3: May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ABC family. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: integral to plasma membrane; membrane; plasma membrane. Molecular Function: anion transmembrane-transporting ATPase activity; ATP binding; ATPase activity, coupled to transmembrane movement of substances; bile acid-exporting ATPase activity; organic anion transmembrane transporter activity. Biological Process: bile acid and bile salt transport; metabolic process; transmembrane transport; transport

0.1 mg

190 USD