protein

Adam12 Immunizing Peptide

MBS427679

0.1 mg

190 USD

Peptide

Adam12 Immunizing Peptide

Adam12

Adam12; a disintegrin and metallopeptidase domain 12 (meltrin alpha); KIAA4001; Mltna; mKIAA4001; ADAM 12; OTTMUSP00000023508; a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase domain 12 (meltrin alpha); disintegrin and meta; Adam12 (mouse)

disintegrin and metalloproteinase domain-containing protein 12 preproprotein; Disintegrin and metalloproteinase domain-containing protein 12; disintegrin and metalloproteinase domain-containing protein 12; a disintegrin and metallopeptidase domain 12 (meltrin alpha); Meltrin-alpha

Adam12

Adam12; Adam12; Mltna; Mltna; ADAM 12

ADA12_MOUSE

Mouse, Rat, Pig

903

KKTTMEKLRCVHP

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

117606341

NP_031426.2

NM_007400.2

98,504 Da

Signal Transduction Pathway (1366876); Signaling By EGFR Pathway (1366877); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein that localizes to the cell surface. About a third of the mice lacking the encoded protein die before weaning. Overexpression of the encoded protein in a mouse model of Duchenne muscular dystrophy alleviates the muscle pathology by preventing cell necrosis and inflammation. [provided by RefSeq, May 2016]

ADAM12: contains a disintegrin and metalloprotease (ADAM) domain 12, which is a member of the ADAM protein family. Involved in skeletal muscle regeneration, specifically at the onset of cell fusion, and the differentiation of macrophage-derived giant cells (MGC) and osteoclasts. 2 alternative splicing isoforms have been described: a shorter secreted form and a longer membrane-bound form. The shorter form stimulates myogenesis. Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Membrane protein, integral; Protease. Cellular Component: integral to membrane; membrane; mitochondrion; nucleoplasm; plasma membrane. Molecular Function: hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; protein binding; SH3 domain binding; zinc ion binding. Biological Process: cell adhesion; proteolysis

0.1 mg

190 USD