product summary
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company name :
MyBioSource
product type :
protein
product name :
Tph2 Immunizing Peptide
catalog :
MBS427520
quantity :
0.1 mg
price :
190 USD
more info or order :
product information
catalog number :
MBS427520
products type :
Peptide
products full name :
Tph2 Immunizing Peptide
products short name :
Tph2
products name syn :
Tph2; tryptophan hydroxylase 2; AU043594; MGC159133; Ntph; OTTMUSP00000022885; neuronal tryptophan hydroxylase; tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; Tph2 (mouse)
other names :
tryptophan 5-hydroxylase 2; Tryptophan 5-hydroxylase 2; tryptophan 5-hydroxylase 2; tryptophan hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2
products gene name :
Tph2
other gene names :
Tph2; Tph2; Ntph; AU043594; Ntph
uniprot entry name :
TPH2_MOUSE
reactivity :
Mouse
sequence length :
488
sequence :
C-SLTQNKAIKSEDK
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi gi num :
148540044
ncbi acc num :
NP_775567.2
ncbi gb acc num :
NM_173391.3
ncbi mol weight :
55,859 Da
ncbi pathways :
Amine-derived Hormones Pathway (1367834); Melatonin Biosynthesis, Tryptophan = Serotonin = Melatonin Pathway (421793); Melatonin Biosynthesis, Tryptophan = Serotonin = Melatonin Pathway (468230); Metabolic Pathways (132962); Metabolism Pathway (1367614); Metabolism Of Amino Acids And Derivatives Pathway (1367816); SIDS Susceptibility Pathways (198328); Serotonergic Synapse Pathway (525339); Serotonin And Melatonin Biosynthesis Pathway (1367838); Tryptophan Metabolism Pathway (83163)
uniprot summary :
TPH2: an enzyme that is rate-limiting in the biosynthesis of serotonin. It catalyzes the biopterin dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Its expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells. Two alternatively spliced isoforms have been described. Isoform 2 appears to be expressed exclusively in the brain, and is expressed at significantly higher levels in the raphe nuclei than isoform 1. Protein type: Amino Acid Metabolism - tryptophan; EC 1.14.16.4; Oxidoreductase. Cellular Component: neuron projection. Molecular Function: amino acid binding; iron ion binding; metal ion binding; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen; tryptophan 5-monooxygenase activity. Biological Process: aromatic amino acid family metabolic process; metabolic process; serotonin biosynthetic process; serotonin biosynthetic process from tryptophan
size1 :
0.1 mg
price1 :
190 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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