catalog number :
MBS426989
products full name :
ADAM17/TACE Immunizing Peptide
products short name :
ADAM17/TACE
products name syn :
ADAM17; TACE; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor; alpha; converting enzyme); CSVP; cSVP; CD156b; CD156b; MGC71942; TACE; cSVPADAM metallopeptidase domain 17; TNF-alpha converting enzyme; a disintegrin and metalloproteinas
other names :
disintegrin and metalloproteinase domain-containing protein 17 preproprotein; Disintegrin and metalloproteinase domain-containing protein 17; disintegrin and metalloproteinase domain-containing protein 17; TNF-alpha convertase; snake venom-like protease; TNF-alpha converting enzyme; ADAM metallopeptidase domain 18; tumor necrosis factor, alpha, converting enzyme; ADAM metallopeptidase domain 17; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD_antigen: CD156b
products gene name :
ADAM17
other gene names :
ADAM17; ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B; NISBD1; CSVP; TACE; ADAM 17
uniprot entry name :
ADA17_HUMAN
reactivity :
Human, Mouse, Rat
sequence :
LQRQNRVDSKETEC
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
other info1 :
Corresponding Antibody: Catalog #MBS421126
ncbi acc num :
NP_003174.3
ncbi gb acc num :
NM_003183.4
ncbi mol weight :
78,543 Da
ncbi pathways :
Activated NOTCH1 Transmits Signal To The Nucleus Pathway 576270!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Apoptosis Pathway 105648!!BDNF Signaling Pathway 712093!!Collagen Degradation Pathway 730309!!Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway 771591!!Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway 771595!!Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway 771593
ncbi summary :
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]