product summary
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company name :
MyBioSource
product type :
protein
product name :
GAD2 / GAD65 Immunizing Peptide
catalog :
MBS426951
quantity :
0.1 mg
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS426951
products type :
Peptide
products full name :
GAD2 / GAD65 Immunizing Peptide
products short name :
GAD2 / GAD65
products name syn :
GAD2; GAD65; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); RP11-420F12.2; MGC161605; MGC161607; Glutamate decarboxylase-2 (pancreas); gl; GAD2 / GAD65
other names :
glutamate decarboxylase 2; Glutamate decarboxylase 2; glutamate decarboxylase 2; glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
products gene name :
GAD2
products gene name syn :
GAD65
other gene names :
GAD2; GAD2; GAD65; GAD65; GAD-65
uniprot entry name :
DCE2_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence length :
585
sequence :
C-TLEDNEERMSRLSK
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi gi num :
4503875
ncbi acc num :
NP_000809.1
ncbi gb acc num :
NM_000818.2
ncbi mol weight :
65,411 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway (198783); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Biogenic Amine Synthesis Pathway (198793); Butanoate Metabolism Pathway (83007); Butanoate Metabolism Pathway (391); GABA (gamma-Aminobutyrate) Shunt Pathway (413433); GABA (gamma-Aminobutyrate) Shunt Pathway (468220); GABA Synthesis Pathway (1268775); GABA Synthesis, Release, Reuptake And Degradation Pathway (1268774)
ncbi summary :
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
uniprot summary :
GAD2: Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family. Protein type: Lyase; Other Amino Acids Metabolism - beta-alanine; EC 4.1.1.15; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - alanine, aspartate and glutamate; Other Amino Acids Metabolism - taurine and hypotaurine. Chromosomal Location of Human Ortholog: 10p11.23. Cellular Component: axon; cell junction; cytosol; Golgi membrane; perinuclear region of cytoplasm; plasma membrane; presynaptic membrane; synaptic vesicle membrane. Molecular Function: glutamate binding; glutamate decarboxylase activity; protein binding; protein heterodimerization activity; pyridoxal phosphate binding. Biological Process: glutamate decarboxylation to succinate; neurotransmitter biosynthetic process; neurotransmitter secretion; response to drug; synaptic transmission
size1 :
0.1 mg
price1 :
190 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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