catalog number :
MBS426881
products full name :
ADAM33 Immunizing Peptide
products short name :
ADAM33
products name syn :
ADAM33; a disintegrin and metalloproteinase domain 33; HGNC: 15478; DJ964F7.1; DKFZp434K0521; FLJ35308; FLJ36751; MGC71889; a disintegrin and metalloprotease 33; disintegrin and reprolysin metalloproteinase family protein; metalloprotease disintegrin; ADAM
other names :
disintegrin and metalloproteinase domain-containing protein 33 isoform alpha preproprotein; Disintegrin and metalloproteinase domain-containing protein 33; disintegrin and metalloproteinase domain-containing protein 33; ADAM metallopeptidase domain 33
products gene name :
ADAM33
other gene names :
ADAM33; ADAM33; C20orf153; DJ964F7.1; C20orf153; ADAM 33
uniprot entry name :
ADA33_HUMAN
sequence :
CQSRRCRKNAFQEL
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi acc num :
NP_079496.1
ncbi gb acc num :
NM_025220.4
ncbi mol weight :
32,554 Da
ncbi summary :
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
uniprot summary :
ADAM33: Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Protease; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: integral to membrane. Molecular Function: metalloendopeptidase activity; protein binding; zinc ion binding. Biological Process: proteolysis