protein

ANGPTL3 Immunizing Peptide

MBS426847

0.1 mg

190 USD

Blocking Peptide

ANGPTL3 Immunizing Peptide

[ANGPTL3]

[ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin 5]

[angiopoietin-related protein 3 preproprotein; Angiopoietin-related protein 3; angiopoietin-related protein 3; angiopoietin like 3; Angiopoietin-5; ANG-5]

[ANGPTL3]

[ANGPTL3; ANGPTL3; ANL3; ANG-5; FHBL2; ANGPT5; ANGPT5; ANG-5]

ANGL3_HUMAN

460

C-EDQYKQLNQQHSQ

100 ug of Lyophilized peptide , formulation 5pmol/uL in 5% (v/v) acetonitrile/H20.

Shipped at ambient temperature, store at -20°C

Reconstitution: Reconstitute pellet in distilled water where required. For blocking studies, reconstitute pellet in 200 uL distilled water to obtain a 0.5 mg/mL peptide solution.

The peptide eas used in the production of MBS426847 - Goat Anti-ANGPTL3 Antibody. It is currently untested in blocking applications.

7656888

NP_055310.1

NM_014495.3

Integrins In Angiogenesis Pathway (137999)

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

ANGPTL3: Defects in ANGPTL3 are the cause of familial hypobetalipoproteinemia type 2 (FHBL2); also called combined hypobetalipoproteinemia familial. FHBL2 is a disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Affected individuals present with combined hypolipidemia, consisting of extremely low plasma levels of LDL cholesterol, HDL cholesterol, and triglycerides. Protein type: Inhibitor; Cell adhesion; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: cell surface; early endosome; extracellular space; Golgi apparatus; lamellipodium. Molecular Function: enzyme inhibitor activity; growth factor activity; heparin binding; integrin binding; phospholipase inhibitor activity. Biological Process: acylglycerol homeostasis; angiogenesis; artery morphogenesis; cell-matrix adhesion; cholesterol homeostasis; cholesterol metabolic process; fatty acid metabolic process; glycerol metabolic process; integrin-mediated signaling pathway; lipid homeostasis; negative regulation of lipoprotein lipase activity; phospholipid catabolic process; phospholipid homeostasis; phospholipid metabolic process; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of lipid catabolic process; response to hormone stimulus; sequestering of lipid; signal transduction. Disease: Hypobetalipoproteinemia, Familial, 2

0.1 mg

190 USD