catalog number :
MBS426837
products full name :
KLK5 Immunizing Peptide
products short name :
KLK5
products name syn :
KLK5; kallikrein-related peptidase 5; KLK-L2; KLKL2; SCTE; kallikrein 5; kallikrein-like protein 2; stratum corneum tryptic enzyme
other names :
kallikrein-5 preproprotein; Kallikrein-5; kallikrein-5; kallikrein related peptidase 5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
products gene name :
KLK5
other gene names :
KLK5; KLK5; SCTE; KLKL2; KLK-L2; SCTE; KLK-L2
uniprot entry name :
KLK5_HUMAN
reactivity :
Human, Rat, Dog, Cow
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi acc num :
NP_036559.1
ncbi gb acc num :
NM_012427.4
ncbi mol weight :
32,019 Da
ncbi summary :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
uniprot summary :
KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily. Protein type: EC 3.4.21.-; Secreted, signal peptide; Protease; Secreted. Chromosomal Location of Human Ortholog: 19q13.33. Cellular Component: extracellular space. Molecular Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: epidermis development; positive regulation of antibacterial peptide production; positive regulation of G-protein coupled receptor protein signaling pathway; proteolysis