protein

Actin-like 7B Immunizing Peptide

MBS426683

0.1 mg

190 USD

Peptide

Actin-like 7B Immunizing Peptide

Actin-like 7B

actin-like 7B; ACTL7B; RP11-3J11.2; actin-like 7-beta; Actin-like 7B; Actin-like 7B

actin-like protein 7B; Actin-like protein 7B; actin-like protein 7B; actin like 7B; Actin-like-7-beta

ACTL7B

ACTL7B; ACTL7B; Tact1

ACL7B_HUMAN

Human

415

C-QLKMKPRKVHKIK

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

5729722

NP_006677.1

NM_006686.3

45,234 Da

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq, Jul 2008]

ACTL7B: is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq, Jul 2008]. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 9q31. Cellular Component: actin cytoskeleton; cytoplasm. Molecular Function: structural constituent of cytoskeleton

0.1 mg

190 USD