protein

Psoriasin / S100A7 Immunizing Peptide

MBS426582

0.1 mg

190 USD

Peptide

Psoriasin / S100A7 Immunizing Peptide

Psoriasin / S100A7

S100A7; S100 calcium binding protein A7 (psoriasin 1); HGNC: 10497; PSOR1; S100A7c; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); psoriasin 1; Psoriasin; Psoriasin; Psoriasin / S100A7

S100 calcium-binding protein A7; Protein S100-A7; protein S100-A7; S100 calcium binding protein A7; Psoriasin; S100 calcium-binding protein A7

S100A7

S100A7; S100A7; PSOR1; S100A7c; PSOR1; S100A7C

S10A7_HUMAN

Human

101

C-HKYTRRDDKIDKP

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4506769

NP_002954.1

NM_002963.2

11,471 Da

Validated Targets Of C-MYC Transcriptional Repression Pathway (169353)

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]

S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular region; focal adhesion; nucleus. Molecular Function: calcium ion binding; protein binding; RAGE receptor binding; zinc ion binding. Biological Process: angiogenesis; defense response to Gram-negative bacterium; epidermis development; innate immune response; keratinocyte differentiation; response to lipopolysaccharide; response to reactive oxygen species; sequestering of metal ion

0.1 mg

190 USD