protein

ABCB8 Immunizing Peptide

MBS426536

0.1 mg

190 USD

Peptide

ABCB8 Immunizing Peptide

ABCB8

ABCB8; ATP-binding cassette, sub-family B (MDR/TAP), member 8; EST328128; M-ABC1; MABC1; ATP-binding cassette, sub-family B, member 8; mitochondrial ABC protein

ATP-binding cassette sub-family B member 8, mitochondrial isoform b; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette sub-family B member 8, mitochondrial; ATP binding cassette subfamily B member 8; Mitochondrial ATP-binding cassette 1; M-ABC1

ABCB8

ABCB8; ABCB8; MABC1; M-ABC1; EST328128; MABC1; M-ABC1

ABCB8_HUMAN

Human

718

C-KKPEGPRSHQHK

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

156105685

NP_009119.2

NM_007188.4

59,383 Da

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC-family Proteins Mediated Transport Pathway (1269904); Mitochondrial ABC Transporters Pathway (1269906); Transmembrane Transport Of Small Molecules Pathway (1269903)

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ABCB8: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. [provided by RefSeq, Jul 2008]. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Mitochondrial; Hydrolase; Transporter. Chromosomal Location of Human Ortholog: 7q36. Cellular Component: ATP-binding cassette (ABC) transporter complex; membrane; mitochondrial envelope; mitochondrial inner membrane; mitochondrion; nucleolus; nucleus. Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances; transporter activity. Biological Process: metabolic process; transmembrane transport; transport

0.1 mg

190 USD