protein

Smooth muscle alpha-actin Immunizing Peptide

MBS426418

0.1 mg

190 USD

Peptide

Smooth muscle alpha-actin Immunizing Peptide

Smooth muscle alpha-actin

ACTA2; actin, alpha 2, smooth muscle, aorta; OTTHUMP00000020042; ACTSA; AAT6; ACTSA; alpha 2 actin; alpha-cardiac actin; growth-inhibiting gene 46; smooth muscle alpha-actin; Smooth muscle alpha-actin; Smooth muscle alpha-actin

actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein

ACTA2

ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS

ACTA_HUMAN

Human, Mouse, Rat, Dog

377

EEEDSTALVC

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4501883

NP_001604.1

NM_001613.2

42,009 Da

Muscle Contraction Pathway (1269868); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (1269870); Striated Muscle Contraction Pathway (198903); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. Protein type: Motility/polarity/chemotaxis; Contractile; Cytoskeletal. Chromosomal Location of Human Ortholog: 10q23.3. Cellular Component: actin cytoskeleton; cytoplasm; cytosol; extracellular space; filopodium; lamellipodium; protein complex; smooth muscle contractile fiber. Molecular Function: ATP binding; protein kinase binding. Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction. Disease: Aortic Aneurysm, Familial Thoracic 6; Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome

0.1 mg

190 USD