protein

ACADM Immunizing Peptide

MBS426384

0.1 mg

190 USD

Peptide

ACADM Immunizing Peptide

ACADM

ACADM; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; RP4-682C21.1; ACAD1; MCAD; MCADH; medium-chain acyl-CoA dehydrogenase; FLJ18227; FLJ93013; FLJ99884; medium-chain specific acyl-CoA dehydrogenase

medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform a; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-CoA dehydrogenase, C-4 to C-12 straight chain

ACADM

ACADM; ACADM; MCAD; ACAD1; MCADH; MCAD

ACADM_HUMAN

Human

421

C-RLIVAREHIDKYKN

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4557231

NP_000007.1

NM_000016.5

47,020 Da

Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway (1270020); Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway (1270021); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045)

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ACADM: This enzyme is specific for acyl chain lengths of 4 to 16. Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD). It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy. Belongs to the acyl-CoA dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Oxidoreductase; Mitochondrial; Lipid Metabolism - fatty acid; EC 1.3.8.7; Carbohydrate Metabolism - propanoate; Other Amino Acids Metabolism - beta-alanine. Chromosomal Location of Human Ortholog: 1p31. Cellular Component: axon; mitochondrial matrix; mitochondrion; nucleus; peroxisome. Molecular Function: acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; identical protein binding. Biological Process: carnitine biosynthetic process; carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; lipid homeostasis; medium-chain fatty acid catabolic process; medium-chain fatty acid metabolic process. Disease: Acyl-coa Dehydrogenase, Medium-chain, Deficiency Of

0.1 mg

190 USD