protein

LTF Immunizing Peptide

MBS426232

0.1 mg

190 USD

Blocking Peptide

LTF Immunizing Peptide

[LTF]

[LTF; lactotransferrin; GIG12; HLF2; LF; growth-inhibiting protein 12; lactoferrin; neutrophil lactoferrin; talalactoferrin]

[lactotransferrin isoform 1 preproprotein; Lactotransferrin; lactotransferrin; lactotransferrin; Growth-inhibiting protein 12; Talalactoferrin]

[LTF]

[LTF; LTF; LF; HLF2; GIG12; HEL110; GIG12; LF; Lactoferrin; Lfcin-H]

TRFL_HUMAN

Goat

Human

710

C-ENYKSQQSSDPDP

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

54607120

NP_002334.2

NM_002343.5

73,161 Da

Amyloid Fiber Formation Pathway (1269169); Disease Pathway (1268854); Immune System Pathway (1269170); Infectious Disease Pathway (1269056); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (1269137); Metabolism Of Proteins Pathway (1268677); Mtb Iron Assimilation By Chelation Pathway (1269143); ROS, RNS Production In Response To Bacteria Pathway (1269138); Response Of Mtb To Phagocytosis Pathway (1269139)

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: Secreted, signal peptide; Protease; EC 3.4.21.-; Secreted. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: cell surface; cytoplasm; extracellular region; extracellular space; nucleus; protein complex; secretory granule; specific granule. Molecular Function: DNA binding; heparin binding; iron ion binding; protein binding; protein serine/threonine kinase activator activity; serine-type endopeptidase activity. Biological Process: activation of NF-kappaB transcription factor; antibacterial humoral response; antifungal humoral response; cell redox homeostasis; cellular protein metabolic process; humoral immune response; innate immune response in mucosa; ion transport; iron assimilation by chelation and transport; negative regulation of apoptosis; negative regulation of ATPase activity; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of viral genome replication; negative regulation of viral reproduction; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of osteoblast differentiation; positive regulation of osteoblast proliferation; positive regulation of toll-like receptor 4 signaling pathway; proteolysis; regulation of cytokine production; regulation of tumor necrosis factor production; retinal homeostasis; transcription, DNA-dependent

0.1 mg

190 USD