protein

Serotonin receptor 1B / HTR1B Immunizing Peptide

MBS426066

0.1 mg

190 USD

Peptide

Serotonin receptor 1B / HTR1B Immunizing Peptide

Serotonin receptor 1B / HTR1B

HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12; Serotonin receptor 1B; Serotonin receptor 1B / HTR1B

5-hydroxytryptamine receptor 1B; 5-hydroxytryptamine receptor 1B; 5-hydroxytryptamine receptor 1B; 5-hydroxytryptamine receptor 1B; S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1B

HTR1B

HTR1B; HTR1B; S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta; HTR1DB; 5-HT-1B; 5-HT1B; 5-HT-1D-beta

5HT1B_HUMAN

Human, Mouse, Rat, Cat, Dog, Pig, Cow

390

C-SNEDFKQAFHK

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4504533

NP_000854.1

NM_000863.2

43,568 Da

Amine Ligand-binding Receptors Pathway (1269553); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Monoamine GPCRs Pathway (198861); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Serotonergic Synapse Pathway (525336)

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015]

5-HT(1B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 6q13. Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane. Molecular Function: drug binding; protein binding; serotonin binding; serotonin receptor activity. Biological Process: bone remodeling; drinking behavior; G-protein coupled receptor internalization; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cAMP biosynthetic process; negative regulation of serotonin secretion; negative regulation of synaptic transmission, GABAergic; negative regulation of synaptic transmission, glutamatergic; protein kinase C activation; regulation of behavior; regulation of dopamine secretion; response to cocaine; response to ethanol; response to mineralocorticoid stimulus; serotonin receptor, adenylate cyclase inhibiting pathway; synaptic transmission; vasoconstriction

0.1 mg

190 USD