protein

ABCD4 Immunizing Peptide

MBS426038

0.1 mg

190 USD

Peptide

ABCD4 Immunizing Peptide

ABCD4

ABCD4; ATP-binding cassette, sub-family D (ALD), member 4; ABC41; EST352188; P70R; P79R; PMP69; PXMP1L; ATP-binding cassette, sub-family D, member 4; peroxisomal membrane protein 1-like; ABCD4

ATP-binding cassette sub-family D member 4; ATP-binding cassette sub-family D member 4; ATP-binding cassette sub-family D member 4; ATP binding cassette subfamily D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69

ABCD4

ABCD4; ABCD4; P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188; PXMP1L; P70R; PXMP1-L; PMP69

ABCD4_HUMAN

Human, Mouse, Rat, Dog

606

C-RDDIDNPDQRISQD

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4826958

NP_005041.1

NM_005050.3

68,597 Da

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway (1270152); Metabolism Pathway (1269956); Metabolism Of Vitamins And Cofactors Pathway (1270144); Metabolism Of Water-soluble Vitamins And Cofactors Pathway (1270145); Peroxisome Pathway (131226); Peroxisome Pathway (131126)

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]

ABCD4: is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]. Protein type: Membrane protein, integral; Transporter, ABC family; Transporter; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: ATP-binding cassette (ABC) transporter complex; endoplasmic reticulum membrane; integral to membrane; lysosomal membrane; peroxisomal membrane; peroxisome. Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances. Biological Process: cobalamin metabolic process; transmembrane transport. Disease: Methylmalonic Aciduria And Homocystinuria, Cblj Type

0.1 mg

190 USD