protein

MMP7 Immunizing Peptide

MBS426016

0.1 mg

190 USD

Peptide

MMP7 Immunizing Peptide

MMP7

MMP7; matrix metalloproteinase 7 (matrilysin, uterine); HGNC: 7174; MMP-7; MPSL1; PUMP-1; matrin; matrix metalloproteinase 7; uterine matrilysin; matrix metallopeptidase 7

matrilysin preproprotein; Matrilysin; matrilysin; matrix metallopeptidase 7; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase

MMP7

MMP7; MMP7; MMP-7; MPSL1; PUMP-1; MPSL1; PUMP1; MMP-7

MMP7_HUMAN

Human

267

C-QKLYGKRSNSRKK

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4505219

NP_002414.1

NM_002423.4

29,677 Da

AGE/RAGE Pathway (698754); Activation Of Matrix Metalloproteinases Pathway (1270258); Alpha6-Beta4 Integrin Signaling Pathway (198807); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (1270247); Collagen Degradation Pathway (1270259); Collagen Formation Pathway (1270245); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Matrix Metalloproteinases Pathway (198900); Syndecan-1-mediated Signaling Events Pathway (138046)

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]

MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family. Protein type: Secreted, signal peptide; Secreted; EC 3.4.24.23; Protease. Chromosomal Location of Human Ortholog: 11q22.2. Cellular Component: cell surface; extracellular region; extracellular space; proteinaceous extracellular matrix. Molecular Function: heparin binding; metalloendopeptidase activity; serine-type endopeptidase activity; zinc ion binding. Biological Process: aging; collagen catabolic process; extracellular matrix disassembly; maternal process involved in pregnancy; proteolysis; response to nutrient levels

0.1 mg

190 USD