protein

PLA2G1B Immunizing Peptide

MBS425980

0.1 mg

190 USD

Peptide

PLA2G1B Immunizing Peptide

PLA2G1B

PLA2G1B; phospholipase A2, group IB (pancreas); MGC119834; MGC119835; PLA2; PLA2A; PPLA2; phospholipase A2, group IB;

phospholipase A2; Phospholipase A2; phospholipase A2; phospholipase A2 group IB; Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B

PLA2G1B

PLA2G1B; PLA2G1B; PLA2; PLA2A; PPLA2; PLA2; PLA2A; PPLA2

PA21B_HUMAN

Human, Dog

148

NKAHKNLDTKKYCQS

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

4505847

NP_000919.1

NM_000928.2

16,360 Da

Acyl Chain Remodelling Of PC Pathway (1270062); Acyl Chain Remodelling Of PE Pathway (1270058); Acyl Chain Remodelling Of PG Pathway (1270069); Acyl Chain Remodelling Of PI Pathway (1270067); Acyl Chain Remodelling Of PS Pathway (1270065); Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (366); Ether Lipid Metabolism Pathway (82990); Ether Lipid Metabolism Pathway (365); Fat Digestion And Absorption Pathway (194385)

This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]

PLA2G1B: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Belongs to the phospholipase A2 family. Protein type: Lipid Metabolism - alpha-linolenic acid; Phospholipase; Lipid Metabolism - arachidonic acid; DNA replication; Secreted, signal peptide; EC 3.1.1.4; Lipid Metabolism - linoleic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Secreted. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: cell surface; extracellular region; extracellular space; secretory granule. Molecular Function: bile acid binding; calcium ion binding; calcium-dependent phospholipase A2 activity; phospholipase A2 activity; receptor binding. Biological Process: actin filament organization; activation of MAPK activity; activation of NF-kappaB transcription factor; activation of phospholipase A2; antibacterial humoral response; arachidonic acid secretion; cellular response to insulin stimulus; defense response to Gram-positive bacterium; fatty acid biosynthetic process; glucose transport; innate immune response in mucosa; interleukin-8 production; leukotriene biosynthetic process; multicellular organismal lipid catabolic process; neutrophil chemotaxis; neutrophil mediated immunity; phosphatidic acid biosynthetic process; phosphatidylcholine metabolic process; positive regulation of DNA replication; positive regulation of fibroblast proliferation; positive regulation of immune response; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; signal transduction

0.1 mg

190 USD