NMDA receptor 1 / GRIN1 Immunizing Peptide | MyBioSource MBS425917 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

NMDA receptor 1 / GRIN1 Immunizing Peptide

catalog :

MBS425917

quantity :

0.1 mg

price :

190 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS425917

products type :

Peptide

products full name :

NMDA receptor 1 / GRIN1 Immunizing Peptide

products short name :

NMDA receptor 1 / GRIN1

products name syn :

GRIN1; NMDA receptor 1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; NMDA1; NMDAR1; NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1; glutamate [NMDA] receptor subunit zeta 1; NMDA receptor 1 / GRIN1

other names :

glutamate receptor ionotropic, NMDA 1 isoform GluN1-4a; Glutamate receptor ionotropic, NMDA 1; glutamate receptor ionotropic, NMDA 1; glutamate ionotropic receptor NMDA type subunit 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1

products gene name :

GRIN1

products gene name syn :

NMDA

other gene names :

GRIN1; GRIN1; NR1; MRD8; GluN1; NMDA1; NMD-R1; NMDAR1; NMDAR1; GluN1; NMD-R1

uniprot entry name :

NMDZ1_HUMAN

reactivity :

Human, Mouse, Rat, Dog

sequence length :

885

sequence :

C-TQERVNNSNKKE

form :

100ug of dried peptide

storage stability :

Shipped at ambient temperature, store at -20 degree C

ncbi gi num :

11496971

ncbi acc num :

NP_000823.4

ncbi gb acc num :

NM_000832.6

ncbi mol weight :

101,851 Da

ncbi pathways :

ARMS-mediated Activation Pathway (1269471); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (1268798); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099)

ncbi summary :

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

uniprot summary :

NMDAR1: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. Three alternatively-spliced isoforms have been described. Protein type: Channel, calcium; Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: cell junction; cell soma; cell surface; dendrite; dendritic spine; endoplasmic reticulum; excitatory synapse; integral to plasma membrane; N-methyl-D-aspartate selective glutamate receptor complex; neuron projection; plasma membrane; postsynaptic density; postsynaptic membrane; synapse; synaptic vesicle; terminal button. Molecular Function: calcium channel activity; calcium ion binding; calmodulin binding; enzyme binding; extracellular-glutamate-gated ion channel activity; glutamate binding; glutamate receptor binding; glycine binding; N-methyl-D-aspartate selective glutamate receptor activity; neurotransmitter binding; protein binding; protein heterodimerization activity; Ras guanyl-nucleotide exchange factor activity; voltage-gated cation channel activity. Biological Process: adult locomotory behavior; calcium ion homeostasis; cation transport; cellular calcium ion homeostasis; cerebral cortex development; conditioned taste aversion; ephrin receptor signaling pathway; ionotropic glutamate receptor signaling pathway; long-term memory; male mating behavior; MAPKKK cascade; negative regulation of neuron apoptosis; olfactory learning; pons maturation; positive regulation of apoptosis; positive regulation of GTPase activity; positive regulation of transcription from RNA polymerase II promoter; prepulse inhibition; propylene metabolic process; protein tetramerization; regulation of axonogenesis; regulation of dendrite morphogenesis; regulation of excitatory postsynaptic membrane potential; regulation of long-term neuronal synaptic plasticity; regulation of membrane potential; regulation of respiratory gaseous exchange; regulation of synaptogenesis; respiratory gaseous exchange; response to amphetamine; response to calcium ion; response to ethanol; response to morphine; rhythmic process; sensory perception of pain; social behavior; suckling behavior; synaptic transmission; synaptic transmission, glutamatergic; visual learning. Disease: Mental Retardation, Autosomal Dominant 8

size1 :

0.1 mg

price1 :

190 USD

more info or order :

MyBioSource product webpage