product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Lubricin / PRG4 Immunizing Peptide
catalog :
MBS425914
quantity :
0.1 mg
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS425914
products type :
Peptide
products full name :
Lubricin / PRG4 Immunizing Peptide
products short name :
Lubricin / PRG4
products name syn :
PRG4; proteoglycan 4; CACP; FLJ32635; HAPO; JCAP; MSF; SZP; bG174L6.2; Jacobs camptodactyly-arthropathy-pericarditis syndrome; articular superficial zone protein; bG174L6.2 (MSF: megakaryocyte stimulating factor); camptodactyly, arthropathy, coxa vara,; Lubricin; Lubricin / PRG4
other names :
proteoglycan 4 isoform A; Proteoglycan 4; proteoglycan 4; proteoglycan 4; Lubricin; Megakaryocyte-stimulating factor; Superficial zone proteoglycan
products gene name :
PRG4
other gene names :
PRG4; PRG4; MSF; SZP; CACP; HAPO; JCAP; MSF; SZP
uniprot entry name :
PRG4_HUMAN
reactivity :
Human
sequence length :
1404
sequence :
DYESFCAEVHNP
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi gi num :
67190163
ncbi acc num :
NP_005798.2
ncbi gb acc num :
NM_005807.3
ncbi mol weight :
146,468 Da
ncbi summary :
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
uniprot summary :
PRG4: Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface. Defects in PRG4 are the cause of camptodactyly- arthropathy-coxa vara-pericarditis syndrome (CACP); also known as Jacobs syndrome. CACP is an autosomal recessive disorder. Individuals with CACP have normal appearing joints at birth but with advancing age develop joint failure associated with noninflammatory synoviocyte hyperplasia and subintimal fibrosis of the synovial capsule. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q25-q31. Cellular Component: extracellular region. Molecular Function: polysaccharide binding; scavenger receptor activity. Biological Process: cell proliferation; immune response; receptor-mediated endocytosis. Disease: Camptodactyly-arthropathy-coxa Vara-pericarditis Syndrome
size1 :
0.1 mg
price1 :
190 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!