product summary
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company name :
MyBioSource
product type :
protein
product name :
CSN2 / TRIP15 Immunizing Peptide
catalog :
MBS425841
quantity :
0.1 mg
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS425841
products type :
Blocking Peptide
products full name :
CSN2 / TRIP15 Immunizing Peptide
products short name :
[CSN2 / TRIP15]
products name syn :
[COPS2; TRIP15; COPS2; CSN2; thyroid receptor interacting protein 15; SGN2; COP9 constitutive photomorphogenic homolog subunit 2; thyroid receptor interacting protein 15; COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis); COP9, subunit 2; CSN2 / TRIP15]
other names :
[COP9 signalosome complex subunit 2 isoform 1; COP9 signalosome complex subunit 2; COP9 signalosome complex subunit 2; COP9 signalosome subunit 2; Alien homolog; JAB1-containing signalosome subunit 2; Thyroid receptor-interacting protein 15; TR-interacting protein 15; TRIP-15]
products gene name :
[COPS2]
products gene name syn :
[CSN2; TRIP15]
other gene names :
[COPS2; COPS2; CSN2; SGN2; ALIEN; TRIP15; CSN2; TRIP15; SGN2; Signalosome subunit 2; TR-interacting protein 15; TRIP-15]
uniprot entry name :
CSN2_HUMAN
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
443
sequence :
C-LNSLNQAVVSKLA
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
other info1 :
Use: The peptide was used in the production of MBS421138-Goat Anti-CSN2/Trip15 Antibody. It is currently untested in blocking applications.
ncbi gi num :
4759264
ncbi acc num :
NP_004227.1
ncbi gb acc num :
NM_004236.3
ncbi mol weight :
52,405 Da
ncbi pathways :
DNA Damage Recognition In GG-NER Pathway (1309113); DNA Repair Pathway (1270350); Formation Of TC-NER Pre-Incision Complex Pathway (1309118); Global Genome Nucleotide Excision Repair (GG-NER) Pathway (1309112); Nucleotide Excision Repair Pathway (1309111); Transcription-Coupled Nucleotide Excision Repair (TC-NER) Pathway (1309117)
uniprot summary :
COPS2: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN- dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1. Belongs to the CSN2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 15q21.2. Cellular Component: cytoplasm; nucleoplasm; signalosome. Molecular Function: protein binding; signal transducer activity; transcription corepressor activity. Biological Process: cell proliferation; cullin deneddylation; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; nucleotide-excision repair, DNA damage recognition; signal transduction; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair
size1 :
0.1 mg
price1 :
190 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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