catalog number :
MBS425780
products full name :
14-3-3 tau / YWHAQ Immunizing Peptide
products short name :
14-3-3 tau / YWHAQ
products name syn :
YWHAQ; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3; 1C5; HS1; 14-3-3 protein T-cell; 14-3-3 protein theta; protein tau; tyrosine 3/tryptophan 5 -monooxygenase activation protein, th; 14-3-3 tau / YWHAQ
other names :
14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
products gene name :
YWHAQ
products gene name syn :
14-3-3 tau
other gene names :
YWHAQ; YWHAQ; 1C5; HS1; 14-3-3
uniprot entry name :
1433T_HUMAN
reactivity :
Human, Mouse, Rat, Dog
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi acc num :
NP_006817.1
ncbi gb acc num :
NM_006826.3
ncbi mol weight :
27,764 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway (1270271); Activation Of BH3-only Proteins Pathway (1270270); Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (1270262); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (1269741); Cell Cycle Checkpoints Pathway (1269742); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463)
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
uniprot summary :
14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 2p25.1. Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex. Molecular Function: protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding. Biological Process: negative regulation of transcription, DNA-dependent; protein targeting; small GTPase mediated signal transduction; substantia nigra development