catalog number :
MBS425506
products full name :
A4GNT / alpha4GNT Immunizing Peptide
products short name :
A4GNT / alpha4GNT
products name syn :
A4GNT; alpha-1,4-N-acetylglucosaminyltransferase; MGC149493; alpha4GnT; alpha4GNT
other names :
alpha-1,4-N-acetylglucosaminyltransferase; Alpha-1,4-N-acetylglucosaminyltransferase; alpha-1,4-N-acetylglucosaminyltransferase; alpha-1,4-N-acetylglucosaminyltransferase
products gene name :
A4GNT
other gene names :
A4GNT; A4GNT; alpha4GnT; Alpha4GnT
uniprot entry name :
A4GCT_HUMAN
reactivity :
Human, Dog, Cow
sequence :
C-PRTYRDLIKGPEGS
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi acc num :
NP_057245.1
ncbi gb acc num :
NM_016161.2
ncbi mol weight :
39,497 Da
ncbi pathways :
Metabolism Of Proteins Pathway (1268677); O-linked Glycosylation Pathway (1268734); O-linked Glycosylation Of Mucins Pathway (1268736); Post-translational Protein Modification Pathway (1268701); Heparan Sulfate Biosynthesis Pathway (545278); Heparan Sulfate Biosynthesis (late Stages) Pathway (545274)
ncbi summary :
This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-- 4Galbeta-- R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008]
uniprot summary :
A4GNT: Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O- glycans. Belongs to the glycosyltransferase 32 family. Protein type: EC 2.4.1.-; Membrane protein, integral; Transferase. Chromosomal Location of Human Ortholog: 3p14.3. Cellular Component: Golgi membrane; integral to membrane; membrane. Molecular Function: acetylglucosaminyltransferase activity. Biological Process: carbohydrate metabolic process; glycoprotein biosynthetic process; negative regulation of epithelial cell proliferation; O-glycan processing; protein amino acid O-linked glycosylation