product summary
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company name :
MyBioSource
product type :
protein
product name :
SAP130 / SF3B3 Immunizing Peptide
catalog :
MBS425440
quantity :
0.1 mg
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS425440
products type :
Peptide
products full name :
SAP130 / SF3B3 Immunizing Peptide
products short name :
SAP130 / SF3B3
products name syn :
SF3B3; SAP130; splicing factor 3b, subunit 3, 130kDa; RSE1; SF3B130; KIAA0017; STAF130; pre-mRNA splicing factor SF3b, 130 kDa subunit; spliceosome-associated protein 130; splicing factor 3b, subunit 3; SF3b130; SAP130 / SF3B3
other names :
splicing factor 3B subunit 3; Splicing factor 3B subunit 3; splicing factor 3B subunit 3; splicing factor 3b subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
products gene name :
SF3B3
products gene name syn :
SAP130
other gene names :
SF3B3; SF3B3; RSE1; SAP130; SF3b130; STAF130; KIAA0017; SAP130; SF3b130; SAP 130
uniprot entry name :
SF3B3_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
1217
sequence :
C-VSKKLEDIRTRYAF
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
ncbi gi num :
54112121
ncbi acc num :
NP_036558.3
ncbi gb acc num :
NM_012426.4
ncbi mol weight :
44,606 Da
ncbi pathways :
Gene Expression Pathway (1269649); Processing Of Capped Intron-Containing Pre-mRNA Pathway (1269688); Spliceosome Pathway (125136); Spliceosome Pathway (124832); Spliceosome, U2-snRNP Pathway (413436); Spliceosome, U2-snRNP Pathway (890599); MRNA Splicing Pathway (1269689); MRNA Splicing - Major Pathway (1269690); MRNA Splicing - Minor Pathway (1269691); MRNA Processing Pathway (198843)
ncbi summary :
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]
uniprot summary :
SF3B3: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. Belongs to the RSE1 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: RNA splicing; RNA-binding; Spliceosome. Chromosomal Location of Human Ortholog: 16q22.1. Cellular Component: nucleolus; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosome; U12-dependent spliceosome. Molecular Function: protein binding; RNA binding. Biological Process: mRNA processing; negative regulation of protein catabolic process; nuclear mRNA splicing, via spliceosome; protein complex assembly; RNA splicing; RNA splicing, via transesterification reactions
size1 :
0.1 mg
price1 :
190 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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