catalog number :
MBS425399
products type :
Blocking Peptide
products full name :
TROP2 Immunizing Peptide
products short name :
[TROP2]
products name syn :
[TROP2; TACSTD2; tumor-associated calcium signal transducer 2; EGP-1; GA733; GA733-1; M1S1; epithelial glycoprotein-1; membrane component, chromosome 1, surface marker 1 (40kD glycoprotein, identified by monoclonal antibody GA733)]
other names :
[tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]
products gene name :
[TACSTD2]
products gene name syn :
[TROP2]
other gene names :
[TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2]
uniprot entry name :
TACD2_HUMAN
sequence :
C-HYEQPTIQIELRQN
form :
100ug of lyophilized peptide, formulation 5pmol/uL in 5% (v/v) acetonitrile/H2O. Reconstitute pellet in distilled water where required. For blocking studies, reconstitute pellet in 200ul distilled water to obtain a 0.5 mg/ml peptide solution.
storage stability :
Shipped at ambient temperature, store at -20°C
tested application :
The peptide was used in the production of MBS425399- Goat Anti-TROP2 Antibody. It is currently untested in blocking applications.
ncbi acc num :
NP_002344.2
ncbi gb acc num :
NM_002353.2
ncbi mol weight :
35,709 Da
ncbi summary :
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
uniprot summary :
TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p32. Cellular Component: basal plasma membrane; cytosol; extracellular space; integral to plasma membrane; lateral plasma membrane; membrane; nucleus. Molecular Function: protein binding; receptor activity. Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation; regulation of epithelial cell proliferation; visual perception. Disease: Corneal Dystrophy, Gelatinous Drop-like