catalog number :
MBS425014
products full name :
P2RX7/P2X7 receptor Immunizing Peptide
products short name :
P2RX7/P2X7 receptor
products name syn :
P2RX7; purinergic receptor P2X; ligand-gated ion channel; 7; MGC20089; P2X7; ATP receptor; P2X purinoceptor 7; P2X7 receptor; P2Z receptor; purinergic receptor P2X7; P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; MGC20089; P2X7; ATP receptor
other names :
P2X purinoceptor 7; P2X purinoceptor 7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 receptor; purinergic receptor P2X7 variant A; purinergic receptor P2X, ligand-gated ion channel, 7; ATP receptor; P2Z receptor; Purinergic receptor
products gene name :
P2RX7
other gene names :
P2RX7; P2RX7; P2X7; P2X7
uniprot entry name :
P2RX7_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
YETNKVTRIQSMNY-C
form :
100ug of dried peptide
storage stability :
Shipped at ambient temperature, store at -20 degree C
other info1 :
Corresponding Antibody: Catalog #MBS421665
ncbi acc num :
NP_002553.2
ncbi gb acc num :
NM_002562.4
ncbi mol weight :
58,239 Da
ncbi pathways :
Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Immune System Pathway 106386!!Inflammasomes Pathway 366166!!Innate Immune System Pathway 106387!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways 366164!!The NLRP3 Inflammasome Pathway 366167
ncbi summary :
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]