Goat anti-c-FOS (aa283-295) Antibody | MyBioSource MBS423052 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-c-FOS (aa283-295) Antibody

catalog :

MBS423052

quantity :

0.1 mg

price :

305 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

(0.3ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

product information

catalog number :

MBS423052

products type :

Antibody

products full name :

Goat anti-c-FOS (aa283-295) Antibody

products short name :

[c-FOS]

products name syn :

[activator protein 1, AP-1, cellular oncogene c-fos, C-FOS, FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS), FBJ murine osteosarcoma viral oncogene homolog, FOS, G0/G1 switch regulatory protein 7, p55, proto-oncogene c-Fo]

other names :

[proto-oncogene c-Fos; Proto-oncogene c-Fos; proto-oncogene c-Fos; Fos proto-oncogene, AP-1 trancription factor subunit; Cellular oncogene fos; G0/G1 switch regulatory protein 7]

products gene name :

[FOS]

products gene name syn :

[c-FOS]

other gene names :

[FOS; FOS; p55; AP-1; C-FOS; G0S7]

uniprot entry name :

FOS_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Cat, Dog, Pig, Cow

sequence length :

380

sequence :

SETARSVPDMDLS

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 37kDa band observed in lysates of cell line HeLa (calculated MW of 40.7kDa according to NP_005243.1). Recommended concentration: 0.3-1ug/ml. Primary incubation was 1 hour. IHC: Paraffin embedded Human Tonsil. Recommended concentration: 5ug/ml

image1 heading :

Western Blot (WB)

other info1 :

Immunogen: Peptide with sequence C-SETARSVPDMDLS, from the internal region of the protein sequence according to NP_005243.1. Epitope: Internal region

ncbi gi num :

4885241

ncbi acc num :

NP_005243.1

ncbi gb acc num :

NM_005252.3

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); Activated TLR4 Signalling Pathway (1269236); Activation Of The AP-1 Family Of Transcription Factors Pathway (1269218); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Apoptosis Pathway (83060); Apoptosis Pathway (470); Apoptosis Modulation And Signaling Pathway (198822); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492)

ncbi summary :

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

uniprot summary :

Fos: a proto-oncogenic transcription factor of the bZIP family. Dimerizes with proteins of the JUN family, thereby forming the transcription factor complex AP-1. FOS proteins function as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of FOS has also been associated with apoptotic cell death. Expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. Protein type: DNA-binding; Motility/polarity/chemotaxis; Oncoprotein; Transcription factor. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: nucleoplasm; nucleus. Molecular Function: protein binding; transcription factor activity; transcription factor binding. Biological Process: DNA methylation; inflammatory response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription factor activity; regulation of transcription from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway

size1 :

0.1 mg

price1 :

305 USD

more info or order :

MyBioSource product webpage