antibody

Goat anti-ABCC9 / SUR2 Antibody

MBS422891

0.1 mg

225 USD

polyclonal

goat

nonconjugated

human, dog, cow

ELISA, enzyme immunoassay

Antibody

Goat anti-ABCC9 / SUR2 Antibody

ABCC9/SUR2

ABC37; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette; sub-family C (CFTR/MRP); member 9; CMD1O; FLJ36852; sulfonylurea receptor 2; sulfonylurea receptor 2A; SUR2; ABCC9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; ABC37; CMD1O; FLJ36852; SUR2; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; sulfonylurea receptor 2; sulfonylurea receptor 2A

ATP-binding cassette sub-family C member 9 isoform SUR2A; ATP-binding cassette sub-family C member 9; ATP-binding cassette sub-family C member 9; sulfonylurea receptor 2; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Sulfonylurea receptor 2

ABCC9

ABCC9; ABCC9; SUR2; ABC37; CANTU; CMD1O; ATFB12; SUR2

ABCC9_HUMAN

Polyclonal

Goat

Human, Dog, Cow

1549

TSEYSINNTGKAD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA)

Western Blot: Preliminary experiments gave an approx 90kDa band in Human Testis lysates and 100kDa in Rat Testis lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 170kDa according to NP_005682.2. The 90kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-TSEYSINNTGKAD, from the internal region of the protein sequence according to NP_005682.2; NP_064693.2. Corresponding Immunizing Peptide: Catalog #MBS427423

Important Note: This antibody is expected to recognize isoforms SUR2A (NP_005682.2) and SUR2B (NP_064693.2).

110832835

NP_005682.2

NM_005691.3

174,425 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!ATP Sensitive Potassium Channels Pathway 366228!!Inwardly Rectifying K+ Channels Pathway 366224!!Neuronal System Pathway 106513!!Potassium Channels Pathway 366221!!Transmembrane Transport Of Small Molecules Pathway 106572

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]

0.1 mg

225 USD