catalog number :
MBS422851
products full name :
Goat anti-SLC6A4 (aa605-618) Antibody
products short name :
SLC6A4
products name syn :
5HT transporter; 5HTT; 5-HTT; 5-HTTLPR; 5-hydroxytryptamine transporter; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163632; OTTHUMP00000163633; SERT; sodium-dependent serotonin transporter; solute carrier family 6 (neurotransmitter transporter; serotonin); member 4; solute carrier family 6 member 4; SLC6A4; Goat Anti-SLC6A4 / 5HTT / SERT; SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; hSERT; 5-hydroxytryptamine transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter; OTTHUMP00000163632; OTTHUMP00000163633; sodium-dependent serotonin transporter; solute carrier family 6 member 4
other names :
sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter; sodium-dependent serotonin transporter; 5HT transporter; serotonin transporter 1; Na+/Cl- dependent serotonin transporter; 5-hydroxytryptamine (serotonin) transporter; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; solute carrier family 6 (neurotransmitter transporter), member 4; 5HT transporter; 5HTT; Solute carrier family 6 member 4
products gene name :
SLC6A4
other gene names :
SLC6A4; SLC6A4; HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; HTT; SERT; 5HTT
uniprot entry name :
SC6A4_HUMAN
reactivity :
Human, Mouse, Rat, Cow
sequence :
KERIIKSITPETPT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 75kDa band observed in Mouse, Small Intestine lysates (calculated MW of 70.3kDa according to Human NP_001036.1 and 70.0kDa according to Mouse NP_034614.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-KERIIKSITPETPT, from the C Terminus of the protein sequence according to NP_001036.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS427572
ncbi acc num :
NP_001036.1
ncbi gb acc num :
NM_001045.5
ncbi mol weight :
74,979 Da
ncbi pathways :
Monoamine Transport Pathway 198851!!SIDS Susceptibility Pathways 198901!!Serotonergic Synapse Pathway 525336!!Serotonin Transporter Activity Pathway 920962!!Synaptic Vesicle Pathway 672457
ncbi summary :
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]