catalog number :
MBS422822
products full name :
Goat anti-Transglutaminase 2 (aa578-591) Antibody
products short name :
Transglutaminase 2
products name syn :
C polypeptide; G-ALPHA-h; GNAH; protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; TG(C); TG2; TGase C; TGase H; TGase-2; TGase-H; TGC; tissue transglutaminase; transglutaminase 2 (C polypeptide; protein-glutamine-gamma-glutamyltransferase); transglutaminase C; transglutaminase H; transglutaminase-2; TGM2; Goat Anti-TGM2; TGM2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); G-ALPHA-h; GNAH; TG2; TGC; C polypeptide; TG(C); TGase C; TGase H; TGase-2; TGase-H; protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; tissue transglutaminase; transglutaminase C; transglutaminase H; transglutaminase-2
other names :
protein-glutamine gamma-glutamyltransferase 2 isoform a; Protein-glutamine gamma-glutamyltransferase 2; protein-glutamine gamma-glutamyltransferase 2; TG(C); TGase C; TGase H; TGase-2; TGase-H; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; epididymis secretory protein Li 45; protein-glutamine-gamma-glutamyltransferase; C polypeptide, protein-glutamine-gamma-glutamyltransferase; transglutaminase 2; Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2
products gene name :
TGM2
other gene names :
TGM2; TGM2; TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h; TG(C); TGC; TGase C; TGase H; TGase-2
uniprot entry name :
TGM2_HUMAN
reactivity :
Human, Mouse, Rat, Pig, Cow
sequence :
ERDLYLENPEIKIR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 80kDa band observed in Mouse and Rat Kidney lysates (calculated MW of 77.3kDa according to Human NP_004604.2 and 77.0kDa according to Mouse NP_033399.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-ERDLYLENPEIKIR, from the internal region of the protein sequence according to NP_004604.2. Corresponding Immunizing Peptide: Catalog #MBS427725
other info2 :
Important Note: This antibody is expected to recognize isoform a (NP_004604.2) only.
ncbi acc num :
NP_004604.2
ncbi gb acc num :
NM_004613.2
ncbi mol weight :
38,671 Da
ncbi pathways :
Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512!!Thromboxane A2 Receptor Signaling Pathway 138060
ncbi summary :
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]