catalog number :
MBS422799
products full name :
Goat anti-NRAP Antibody
products short name :
NRAP
products name syn :
Goat Anti-NRAP Antibody; NRAP; nebulin-related anchoring protein; nebulin-related anchoring protein antibody; NRAP antibody
other names :
nebulin-related-anchoring protein isoform 1; Nebulin-related-anchoring protein; nebulin-related-anchoring protein; nebulin related anchoring protein
products gene name :
NRAP
other gene names :
NRAP; NRAP; N-RAP; N-RAP
uniprot entry name :
NRAP_HUMAN
reactivity :
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Preliminary experiments in Human Heart, Skeletal Muscle and Uterus lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
other info1 :
Immunogen: Peptide with sequence EDTKSQCHVSLD, from the internal region of the protein sequence according to NP_006166.3; NP_932326.2. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize all reported isoforms (NP_006166.3; NP_932326.2).
ncbi acc num :
NP_006166.3
ncbi gb acc num :
NM_006175.4
ncbi mol weight :
192,997 Da
uniprot summary :
NRAP: May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 10q24-q26. Cellular Component: fascia adherens; muscle tendon junction. Molecular Function: actin binding; muscle alpha-actinin binding; zinc ion binding