catalog number :
MBS422776
products full name :
Goat anti-ABCB5 (aa364-378) Antibody
products short name :
ABCB5
products name syn :
ABCB5 P-gp; ABCB5alpha; ABCB5beta; ATP-binding cassette protein; ATP-binding cassette sub-family B member 5; ATP-binding cassette; sub-family B (MDR/TAP); member 5; EST422562; P-glycoprotein ABCB5; ABCB5; Goat Anti-ABCB5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ABCB5alpha; ABCB5beta; EST422562; ABCB5 P-gp; ATP-binding cassette protein; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5
other names :
ATP-binding cassette sub-family B member 5 isoform 1; ATP-binding cassette sub-family B member 5; ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5; ATP-binding cassette protein; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ABCB5 P-gp; P-glycoprotein ABCB5
products gene name :
ABCB5
other gene names :
ABCB5; ABCB5; ABCB5beta; EST422562; ABCB5alpha
uniprot entry name :
ABCB5_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
DKKPSIDNFSTAGYK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 85kDa band observed in lysates of cell lines HeLa and K562 (calculated MW of 139kDa according to NP_001157413.1). Please note that the isoform recognized by this antibody is not fully understood. We appreciate any feedback in the field on these results. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DKKPSIDNFSTAGYK, from the internal region of the protein sequence according to NP_001157413.1; NP_848654.3; NP_001157414.1; NP_001157465.1. Corresponding Immunizing Peptide: Catalog #MBS427415
other info2 :
Important Note: This antibody is expected to recognize reported isoform 1 (NP_001157413.1) or isoform 4 according to UniProtKB (Q2M3G0) only.The immunizing peptide represents part of an extracellular domain.
ncbi acc num :
NP_001157413.1
ncbi gb acc num :
NM_001163941.1
ncbi mol weight :
89,832 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]