catalog number :
MBS422751
products full name :
Goat anti-TNFRSF1A/TNFR1 Antibody
products short name :
TNFRSF1A/TNFR1
products name syn :
TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A; CD120a; FPF; MGC19588; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60; TNF-R1; TNF-RI; TNFR-I; tumor necrosis factor binding protein 1; tumor necrosis factor re; CD120a antibody; FPF antibody; MGC19588 antibody; p55 antibody; p55-R antibody; p60 antibody; TBP1 antibody; TNFAR antibody; TNF-R antibody; TNFR1 antibody; TNF-R1 antibody; TNFR55 antibody; TNF-R55 antibody; TNFR60 antibody; TNFR-I antibody; TNF-RI antibody; TNF-R-I antibody; tumor necrosis factor binding protein 1 antibody; tumor necrosis factor receptor 1A isoform beta antibody; tumor necrosis factor receptor superfamily member 1A antibody; tumor necrosis factor receptor superfamily; member 1A antibody; tumor necrosis factor receptor type 1 antibody; tumor necrosis factor-alpha receptor antibody; TNFRSF1A antibody; TNFRSF1A / TNFR1
other names :
tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1
products gene name :
TNFRSF1A
products gene name syn :
TNFR1
other gene names :
TNFRSF1A; TNFRSF1A; FPF; MS5; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; TNFR1-d2; TNFAR; TNFR1; TNF-R1; TNF-RI; TNFR-I; TBPI
uniprot entry name :
TNR1A_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Rat, Pig
sequence :
SDHEIDRLELQNGR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 52kDa band observed in Human Lung lysates and in lysates of cell lines A549, HepG2 and K562 (calculated MW of 50.5kDa according to NP_001056.1). Recommended concentration: 0.3-1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-SDHEIDRLELQNGR, from the internal region of the protein sequence according to NP_001056.1. Epitope: Internal region
ncbi acc num :
NP_001056.1
ncbi gb acc num :
NM_001065.3
ncbi mol weight :
24,194 Da
ncbi pathways :
Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amyotrophic Lateral Sclerosis (ALS) Pathway (920975); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (198797); Apoptosis Pathway (83060)
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq, Jul 2008]