product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-CHIT1 (aa409-423) Antibody
catalog :
MBS422744
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422744
products type :
Antibody
products full name :
Goat anti-CHIT1 (aa409-423) Antibody
products short name :
CHIT1
products name syn :
CHIT1; chitinase 1 (chitotriosidase); CHI3; CHIT; FLJ00314; MGC125322; OTTHUMP00000217083; OTTHUMP00000217084; OTTHUMP00000217085; chitinase-1; chitotriosidase-1; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase; CHI3 antibody; CHIT antibody; chitinase 1 (chitotriosidase) antibody; chitinase-1 antibody; chitotriosidase-1 antibody; FLJ00314 antibody; MGC125322 antibody; OTTHUMP00000217083 antibody; OTTHUMP00000217084 antibody; OTTHUMP00000217085 antibody; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase antibody; CHIT1 antibody; CHIT1 (aa409-423)
other names :
chitotriosidase-1 isoform 1; Chitotriosidase-1; chitotriosidase-1; chitinase 1; Chitinase-1
products gene name :
CHIT1
other gene names :
CHIT1; CHIT1; CHI3; CHIT; CHITD
uniprot entry name :
CHIT1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human
sequence length :
466
sequence :
EHGPSPGQDTFCQGK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 48kDa band observed in lysates of cell line Daudi (calculated MW of 51.7kDa according to NP_003456.1). Recommended concentration: 1-3ug/ml.
other info1 :
Immunogen: Peptide with sequence EHGPSPGQDTFCQGK, from the internal region (near C Terminus) of the protein sequence according to NP_003456.1. Epitope: Internal region (near C Terminus)
ncbi gi num :
4502809
ncbi acc num :
NP_003456.1
ncbi gb acc num :
NM_003465.2
ncbi mol weight :
49,613 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway (82979); Amino Sugar And Nucleotide Sugar Metabolism Pathway (350); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Carbohydrates Pathway (1269957)
ncbi summary :
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
CHIT1: Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; EC 3.2.1.14; Secreted; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Hydrolase. Chromosomal Location of Human Ortholog: 1q32.1. Cellular Component: extracellular region; extracellular space; lysosome. Molecular Function: chitin binding; chitinase activity; endochitinase activity; hydrolase activity, hydrolyzing O-glycosyl compounds. Biological Process: carbohydrate metabolic process; chitin catabolic process; immune response; polysaccharide catabolic process; response to bacterium. Disease: Chitotriosidase Deficiency
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
related products
browse more products
questions and comments