product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Neurofascin (aa877-890) Antibody
catalog :
MBS422738
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422738
products type :
Antibody
products full name :
Goat anti-Neurofascin (aa877-890) Antibody
products short name :
Neurofascin
products name syn :
NFASC; neurofascin; DKFZp686P2250; FLJ46866; KIAA0756; NF; NRCAML; OTTHUMP00000065316; OTTHUMP00000065319; OTTHUMP00000065323; OTTHUMP00000065324; neurofascin homolog; NFASC; neurofascin; DKFZp686P2250; FLJ46866; KIAA0756; NF; NRCAML; OTTHUMP00000065316; OTTHUMP00000065319; OTTHUMP00000065322; OTTHUMP00000065323; OTTHUMP00000065324; neurofascin homolog
other names :
neurofascin isoform 1; Neurofascin; neurofascin; neurofascin homolog; neurofascin
products gene name :
NFASC
other gene names :
NFASC; NFASC; NF; NRCAML; KIAA0756
uniprot entry name :
NFASC_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
1240
sequence :
NFSPNQTKFTVQRT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 170kDa band observed in Human Lung and Rat Brain lysates (calculated MW of 138kDa according to NP_001005388.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Kirschbaum et al, J Biol Chem. 2009 Oct 16;284(42):28533-42. PMID: 19666467). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-NFSPNQTKFTVQRT, from the internal region of the protein sequence according to NP_001005388.2; NP_001153803.1; NP_001153804.1; NP_055905.2. Corresponding Immunizing Peptide: Catalog #MBS427540
other info2 :
Important Note: This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2;,NP_001153803.1, NP_001153804.1and NP_055905.2 resp).
ncbi gi num :
237858675
ncbi acc num :
NP_001005388.2
ncbi gb acc num :
NM_001005388.2
ncbi mol weight :
142,474 Da
ncbi pathways :
Axon Guidance Pathway 105688!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Developmental Biology Pathway 477129!!Interaction Between L1 And Ankyrins Pathway 161005!!L1CAM Interactions Pathway 161003!!Neurofascin Interactions Pathway 161008
ncbi summary :
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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