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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Slc5a1 (rat) Antibody
catalog :
MBS422677
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
rat
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422677
products type :
Antibody
products full name :
Goat anti-Slc5a1 (rat) Antibody
products short name :
Slc5a1
products name syn :
Slc5a1; solute carrier family 5 (sodium/glucose cotransporter), member 1; MGC93553; Sglt1; Na(+)/glucose cotransporter 1; Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter); high affinity sodium-glucose cotransporter; sodium/glucose cotra; high affinity sodium-glucose cotransporter antibody; MGC93553 antibody; Na(+)/glucose cotransporter 1 antibody; Sglt1 antibody; sodium/glucose cotransporter 1 antibody; solute carrier family 5 (sodium/glucose cotransporter); member 1 antibody; solute carrier family 5; member 1 antibody; Solute carrier family 5; member alpha 1 (Na+/glucose cotransporter) antibody; Slc5a1 antibody; Slc5a1 (rat)
other names :
sodium/glucose cotransporter 1; Sodium/glucose cotransporter 1; sodium/glucose cotransporter 1; solute carrier family 5 member 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1
products gene name :
Slc5a1
other gene names :
Slc5a1; Slc5a1; SGLT1; SGLT1a; Sglt1; Na(+)/glucose cotransporter 1
uniprot entry name :
SC5A1_RAT
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Rat; Expected from sequence similarity: Rat
sequence length :
665
sequence :
KDTIEIDAEAPQKEK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 4000. Immunohistochemistry: Cryosections of paraformaldehyde fixed Rat Kidney shows strong staining of the brush-border in proximal straight tubules (S3 segments). Cryosections of paraformaldehyde fixed Rat Small Inteestines shows staining of the brush-border of absorptive cells. Recommended concentration, 20-30ug/ml. Data provided by Ivana Vrhovac, B. Sc. and Ivan Sabolic, M.D., Ph.D., IMROH, Zagreb, Croatia. Western Blot: Approx 75-80kDa band observed in isolated Brush Border Membranes (BBM) of female Rat Kidney and approx 80kDa in BBM of female Rat Small Intestine (calculated MW of 73.1kDa according to NP_037165.1). Recommended concentration: 1-3ug/ml. Data provided by Ivana Vrhovac, B. Sc. And Ivan Sabolic, M. D. , Ph. D. , IMROH, Zagreb, Croatia.
other info1 :
Immunogen: Peptide with sequence C-KDTIEIDAEAPQKEK, from the internal region of the protein sequence according to NP_037165.1. Epitope: Internal region
ncbi gi num :
6981552
ncbi acc num :
NP_037165.1
ncbi gb acc num :
NM_013033.2
ncbi mol weight :
73,066 Da
ncbi pathways :
Bile Secretion Pathway (193141); Bile Secretion Pathway (193095); Carbohydrate Digestion And Absorption Pathway (170716); Carbohydrate Digestion And Absorption Pathway (170654); Hexose Transport Pathway (1376704); Metabolism Pathway (1377550); Metabolism Of Carbohydrates Pathway (1377551); Mineral Absorption Pathway (212234); Mineral Absorption Pathway (212220); Na+-dependent Glucose Transporters Pathway (1376710)
ncbi summary :
catalyzes sodium dependent glucose transport; plays a role in sugar absorption in the small intestine and reabsorption of sugars in the kidney [RGD, Feb 2006]
uniprot summary :
SLC5A1: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. Expressed mainly in intestine and kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral. Cellular Component: apical plasma membrane; brush border; brush border membrane; integral to plasma membrane; intercellular junction. Molecular Function: glucose transmembrane transporter activity; glucose:sodium symporter activity. Biological Process: D-glucose absorption; glucose transport; intestinal absorption; metanephros development; sodium ion transport
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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