catalog number :
MBS422618
products full name :
Goat anti-SON Antibody
products short name :
SON
products name syn :
SON; SON DNA binding protein; BASS1; C21orf50; DBP-5; FLJ21099; FLJ33914; KIAA1019; NREBP; Bax antagonist selected in Saccharomyces 1; NRE-binding protein; OTTHUMP00000197908; OTTHUMP00000198934; negative regulatory element-binding protein;; SON; SON DNA binding protein; BASS1; C21orf50; DBP-5; FLJ21099; FLJ33914; KIAA1019; NREBP; SON3; Bax antagonist selected in Saccharomyces 1; NRE-binding protein; OTTHUMP00000197908; OTTHUMP00000198934; negative regulatory element-binding protein; protein DBP-5; protein SON
other names :
protein SON isoform B; Protein SON; protein SON; NRE-binding protein; Bax antagonist selected in Saccharomyces 1; negative regulatory element-binding protein; SON DNA binding protein; Bax antagonist selected in saccharomyces 1; BASS1; Negative regulatory element-binding protein; NRE-binding protein; Protein DBP-5; SON3
other gene names :
SON; SON; SON3; BASS1; DBP-5; NREBP; C21orf50; C21orf50; DBP5; KIAA1019; NREBP; BASS1; NRE-binding protein
uniprot entry name :
SON_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 35kDa band in Human, Mouse and Rat Heart lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 250kDa according to NP_115571.1. The 35kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence KSRCVSVQTDPTD, from the N Terminus of the protein sequence according to NP_115571.1; NP_620305.1. Corresponding Immunizing Peptide: Catalog #MBS427489
other info2 :
Important Note: This antibody is expected to recognize reported isoforms B (NP_115571.1) and F (NP_620305.1).
ncbi acc num :
NP_115571.1
ncbi gb acc num :
NM_032195.1
ncbi mol weight :
247,823 Da
ncbi summary :
This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]